Overview of Retail Industry in India

The Indian Retail Industry is one of the largest and fastest growing among all the other industries in the world. It has emerged as one of the most dynamic and fast-paced industries because of the entry of many new private players and their increasing participation accounting more than 10% of the country’s Gross Domestic Product (GDP) & 8% of the employment. So, it is said that India is the world’s fifth largest retail destination globally as this field showing gradually inching its way towards becoming the next boom industry.

India’s price competitiveness attracts large retail players to use it as a sourcing base. But all players have not yet succeeded because of the heavy initial investments that are required to compete among other competitor companies to remain ahead in the long run. Retail Industry is not only an essential part of our economic structure but also mould our lifestyle. The modern retail account to only 10% accounts of the market value of $600 Billion but is expected to increase to 15%-18% by 2020 driven by income growth, urbanization and attitudinal shifts.

In the last 15 years, the sector has witnessed a CAGR of 7.46% and is expected to show more than 16.5% compounded annual growth in the next 5 years by 2020.

Retail Classification:

The Indian Retail industry can be broadly classified into two categories namely- Organized and Unorganized retail. Organized retail – Organized traders/retailers, who are licensed for trading activities and registered to pay taxes to the government. Unorganized retail – It consists of unauthorized small shops – conventional Kirana shops, general stores, corner shops among various other small retail outlets – but remain as the radiating force of Indian retail industry.

The Indian Retail sector has come off age and has gone through a major transformation over the last decade with a noticeable shift towards an organized retailing. As of now, the organized retail sector has contributed to 8% of the total trade and is expected to reach to 24% in the next five years. Healthy economic growth, changing demographic profile, increase in disposable incomes, urbanization, growing & changing consumer tastes and preferences are some of the key factors for driving growth in the organized retail sector market in India.

Apart from this, India has been ranked 3rd in the world after China and Brazil in terms of Net Retail Sales as it has been noticed that Food and Grocery account for close to 70% of the total sales in India and Jewellery account close to 6% which is expected to increase to 8% by 2020.

Key Growth Drivers of Retail Industry in India

Nuclearization of Families
An Increase in households incomes
Large working population
Reasonable Real estate prices
Increase in disposable income and customer aspiration
Demand as well as increase in expenditure for luxury items
Growing preference for branded products and higher aspirations
Growing liberalization of the FDI policy in the past decade
Increasing urbanization
The overall retail market of India has the potential to grow from $630 billion to $1,100-1,200 billion by 2020 as the Indian Retail sector will reap the benefits of a large and young population adding to the workforce, 70 per cent increase in income levels, Rapid urbanization and growing trend towards nuclear families, new technology and lifestyle trends creating replacement demand, etc.

Although the opportunity is massive, Indian retailers would need to transform themselves to win as with the GST coming in; productivity will go up along with manufacturing and retailing. With that we can participate in the consumption and growth story in India too.

The Road Ahead:

E-commerce is expanding steadily in the country due to which it is probably creating the biggest revolution in the Indian retail industry and this trend would continue in the years to come.
Organized retail is a new phenomenon in India and the market is growing very rapidly. The middle class growing very rapidly that is an important factor which is contributing in the growth of Indian retail sector. According to the report up to 2030, it is estimated that 21 million household will be converted into 91 million households who are in ‘middle class’. But for this both organized and unorganized retail companies have to work together to ensure better prospects for the overall retail industry in India while generating new benefits for their customers.

Enhanced Killing of TNBC Cells by Oncolytic Viruses

A diagnosis of triple-negative breast cancer (TNBC) means that the three most common types of receptors contributing to most breast cancer growth, estrogen, progesterone, and the HER-2/neu gene, are absent in the cancer tumor. Since the tumor cells lack the necessary receptors, common treatments such as hormone therapy and drugs that target estrogen, progesterone, and HER-2 are ineffective.

TNBC, which accounts for 10% -20.8% of all breast cancer pathological types, has special biological behavior and clinical pathological characteristics, and is more common in premenopausal women and obese people.

TNBC has the following characteristics:

High invasiveness with a high possibility to transfer to lungs and brain;

Risks of a relapse, 1-3 years is the peak period of relapse;

Low survival rate;

High tendency of mutation leading to the development of resistance.

For the treatment of triple-negative breast cancer, traditional methods include chemotherapy, surgery and radiotherapy. Besides, recent research shows that oncolytic virus combined immunotherapy may serve as a novel treatment with improved safety and efficiency.

Surgery

Surgery is the best treatment for local TNBC. Early TNBC is commonly suggested to receive breast-conserving surgery combined with radiation therapy, while high-risk patients with positive or unknown margins are advocated to have radical mastectomy.

Radiotherapy

Radiotherapy can be used as an important method for locally controlling TNBC. It is generally implemented after surgery. Postoperative combined radiotherapy can minimize the risk of local recurrence of TNBC. It is often applied to early TNBC.

Chemotherapy

Common chemotherapy regimens are adjuvant chemotherapy and neoadjuvant chemotherapy.

Chemotherapy can be administered in the neoadjuvant setting. Women with inoperable breast cancer may undergo neoadjuvant chemotherapy in hopes that it shrinks the tumor so it can be surgically removed, sparing the patient from having to undergo a mastectomy. Adjuvant chemotherapy refers to medicines administered after surgery for the treatment of breast cancer, which is designed to prevent recurrence of the disease, particularly distant recurrence.

Oncolytic virus combined immunotherapy

In recent years, immunotherapy has taken a wave in the field of cancer and has become a new means of treating cancer with world-renowned results. On March 8, 2019, Food and Drug Administration (FDA) approved Atezolizumab, the world’s first drug for immunotherapy of TNBC. Then it approved Atezolizumab and Nab-Paclitaxel to treat patients with PD-L1 positive and unresectable locally advanced TNBC.

However, the pace of immunotherapy does not stop there. Oncolytic viruses (OVs), tumor-killing viruses that have the ability to replicate, become the key to open the new door of TNBC immunotherapy. In recent years, it has received extensive attention in tumor research for its innovation and excellent curative effect.

Given that OVs can induce anti-tumor immunity, a scientific study hopes to prove that these viruses help to make TNBC patients more sensitive to immunotherapy. This study establishes a mouse model that mimics the treatment process of newly diagnosed TNBC patients. In the time window of diagnosis and surgical resection, OVs therapy is inserted as a neoadjuvant treatment plan. After the surgery, OVs are combined with immunotherapy to make TNBC patients sensitive to immune checkpoint, thus to prevent recurrence. The results of this study show that oncolytic virus combined with immune checkpoint inhibitor therapy brings new hope for the treatment of TNBC, and it might become an effective means of tumor treatment.

Recently, the treatment of both early and advanced TNBC has seen significant improvements in response rates and survival outcomes. However, more researches are still required to explore more about oncolytic viral immunotherapy.

Marriage counselor Den Haag suggests not to extend any fight & make the end with a smile

You can now make a healthier relation with relationship therapy. You might have come across many who are and so they serve to be the crucial key elements for each other. Both of them have two hands so they complement each other. Now, a relation is complete when couple get equally attaches with each other. As such, their relation is never prone to break or to set apart. So, the first duty of them is to be responsible for the relation and stick with their spouse at any cost and condition. This will happen over time but most crucially the thing is to build any relation in two with the help of a Marriage Counselor Den Haag.

Reconciling a relationship through therapy

Since, you both have to be together, a relationship cannot be breakage prone. Even if there are fallouts and fights in every relation, but the partners should ensure that these are only fights and so shouldn’t last for prolonged time. There shouldn’t be any glimpse after flight and should end it to ensure everything’s fine. The quick you recover from the fight, you’ll find your relation powerful and stronger. In every relationship, each one are strength to one another and so you must know this clearly well.

Finding a better solution through relationship counseling

After your partner realizes how much you love, you’ll like the same and feel the same back to you. Here, the marriage counselors would suggest you not to extend any fights and make the end with smile. Here, communication serves as the key of any fallout and over silly matters who use to fallout. Further, there is no strong back ground or definite reasons over the difference and so is some serious problems but the experience of a Relationship Counselling Den Haag service will surely help you reduce the issue and you’ll find a better solution.

Build one another to trust

After you have made up your mind to sort out issues, you don’t need couple therapist or anyone else. This will wholly depend on you and your partner’s good intention to sort things out. Trust is the root of any relation and so it is important that you build one another to trust each other. Also, you shouldn’t break that tryst and make anything that can harm that trust. When you’re expecting your partner to be loyal for you, you’ll expect the same from you. For instance: you can hold his/her hand in time of anxiety and stress and be patience. In order to keep a relation, healthy patience is needs along with mental and moral support as this tells the untold truth that becomes a lifetime asset.

Leading a happy life without any negative effects

As per the Marriage Counselor Den Haag, fallouts are inseparable part of life for any couple and there is nothing too serious about this. However, this goes beyond control you’d require a therapist for the solution. They help maintain a healthy conversation and control over things while communicating and help you and your partner to be together avoiding all the fights. This will work well to lead a happy life ahead and easier to take in stress without showing negative effects.